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Viagra is among the most popular drugs that are prescribed as treatment for erectile dysfunction in men, and it is also known as Sildenafil (Generic Viagra). Other commercial names are also available. Sildenafil is included in a group of medical remedies called phosphodiesterase type 5 inhibitors, which also contains medications like Stendra (Avanafil), Cialis (Tadalafil) or Levitra (Vardenafil). They basically have the same mechanism of action, but they may differ in terms of their absorption parameters and duration of effects. Sildenafil is also employed for other medical purposes, although less frequently than in the treatment of erectile dysfunction (ED). It is also capable of relieving the symptoms of pulmonary hypertension due to its unique capacity to cause a consistent dilation of blood vessels.
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How does Sildenafil work to help men with erectile dysfunction restore their sexual performance to a level that satisfies their partners?
Sildenafil works by correcting the deficient physiological mechanisms that occur when a man is sexually stimulated. After sufficient sexual arousal, the male brain sends impulses through neural pathways to the penis, where the nerve endings produce NO or nitric oxide, which is a messenger substance. NO works in the blood vessels of specialized penis structures that are capable to receive large amounts of blood, which are called the cavernous bodies. NO stimulates an enzyme to start releasing cGMP, a component that directly causes an erection by dilating the cavernous body blood vessels. This compound is the active chemical that influences the quality of a male erection. However, there is an enzyme called phosphodiesterase type 5 (PDE5), which ends the beneficial effects caused by cGMP by neutralizing and destroying the active compound. Low amounts of cGMP translate into an inability to maintain a satisfactory erection, which makes sexual intercourse problematic and may cause psychological problems such as depression. By inhibiting the PDE5 enzyme, Sildenafil is able to sustain increased levels of cGMP, which results in a normal erection and sexual intercourse. In other words, the inhibition of PDE5 allows for an increased accumulation of cGMP and a constant dilation of blood vessels after sexual intercourse.
Sildenafil has been officially tested and approved as a first-line treatment for erectile dysfunction, but also other medical ailments. Its side effects are usually minor and temporary, if they occur at all. They may include a skin rash, headaches, digestive discomfort or nausea. Don’t hesitate to discuss the effects of Sildenafil treatment on your ED with your doctor to minimize the unpleasant effects and maximize the sexual performance results. Also, if you are taking other drugs for a medical condition, it is mandatory to inform your physician to avoid drug interactions and negative influences during Sildenafil treatment.

Propecia against Har loss
Propecia, also known as Finasteride, is a FDA approved drug used for both the treatment of an enlarged prostate in men and for male pattern baldness. It also has an off-label use as a hormone replacement therapy for male to female transxexuals due to the medication's anti-androgen properties. Propecia is a type two 5-alpa-reductase inhibitor. This medication is developed from a hormone called progesterone. 5-alpa-reductase is an enzyme that works in the body to convert testosterone to dihydrotestosterone.
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Propecia is used as a first line treatment in benign prostatic hyperplasia (BPH). It may be used alone at the recommended dose of 5 mg per day or combined with an alpha-blocker. This medication should be taken with a full glass of water. Propecia does not have an immediate effect – it may take six months or more to determine if the drug is therapeutic in decreasing the size of the prostate. Along with improving BPH, Propecia is also effective in associated symptoms of BPH including difficulty urinating, nocturia, hesitation at the start of urination or decreased urinary flow.
Propecia can also be used as a medical treatment to induce hair growth in men experiencing hair loss and androgenic alopecia. The medication has been shown to be effective in hair growth on both the crown area and the hairline but the most success has been in the crown area. Propecia must be taken consistently and indefinitely since any hair gained or maintained while on the medication is lost within six to twelve months of discontinuing the medication. The most effective dose seems to be at 1 mg per day.
Possible side effects associated with the use of Propecia include impotence, abnormal ejaculation, decreased ejaculatory volume, abnormal sexual function, gynecomastia, erectile dysfunction, ejaculation disorder, and testicular pain. The results have varied on whether Propecia can induce depression and anxiety; therefore, both the provider and patient should monitor for these adverse effects to prevent a decrease in quality of life for the patient. There is also concern by the FDA and other medical groups that this medication may be associated with prostate cancer and male breast cancer but no study has yet been able to prove a link between the two. Your provider should regularly check your PSA level to ensure you are not experiencing any of these side effects so you can be discontinued from the medication immediately if necessary. Propecia should never be taken or even handled by women and children because the medication can be absorbed through the skin. It is considered a category X medication meaning that this medication should not be used in pregnant women because of proven results of harm to the fetus.

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